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Negatively compare synonym7/25/2023 The person's attitude – if the person expects the treatment to work, the chances of a placebo effect are higher, but placebos can still work even if the person is sceptical of success.Generally, injections have a more powerful placebo effect than pills. Research shows that larger sized pills suggest a stronger dose than smaller pills, and taking 2 pills appears to be more potent than swallowing just one. The characteristics of the placebo – if the pill looks real, the person taking it is more likely to believe that it contains an active medicine.Some other things that help the placebo effect to work include: This theory is called 'remembered wellness'. A placebo may help the brain to remember a time before the onset of symptoms, and then bring about change to the body. Altered brain state – research indicates that the brain responds to an imagined scene in much the same way as it responds to an actual visualised scene.Brain chemicals – placebos may trigger the release of the body's own natural pain relievers, the brain chemicals known as endorphins.Reduced anxiety – taking the placebo and expecting to feel better may be soothing and reduce the levels of stress chemicals the body produces, such as adrenaline.For example, they may interpret a sharp pain as an uncomfortable tingling instead. Altered perception – the person's interpretation of their symptoms may change with the expectation of feeling better.Improved diet, regular exercise or rest may be responsible for the easing of their symptoms. A change in behaviour – the placebo may increase a person's motivation to take better care of themselves.A remission (period of time when the symptoms go away) during a course of placebos may be coincidence, and not due to the placebos at all. Remission – the symptoms of some disorders, such as multiple sclerosis and lupus, may come and go.They will resolve by themselves anyway, with or without placebos or medications, and the end of symptoms is just a coincidence. Self-limiting disorders – many conditions, such as the common cold, are self-limiting.Some of the theories that attempt to explain it include: It is still not known exactly how the placebo effect works. Placebos are often used in clinical trials to help understand the real effect of a new treatment – both positive benefits and also possible side effects. ‘Impure placebos’ are medications that have an active effect on the body, but not on the condition being treated. The placebo effect is triggered by the person's belief in the benefit from the treatment and their expectation of feeling better, rather than the characteristics of the placebo. A placebo can be a sugar pill, a water or salt water (saline) injection or even a fake surgical procedure. Placebo is Latin for 'I will please' and refers to a treatment that appears real, but is designed to have no therapeutic benefit. The placebo effect is when a person’s physical or mental health appears to improve after taking a placebo or ‘dummy’ treatment.
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